Murder One is a television drama focusing on two characters.
Character one is Jennifer - a woman in her early 30s who had a bad experience after an ex-boyfriend broke up with her and she was him with his new girlfriend. Since then Jennifer has decided she can never go through that again and so when her relationships end, so do the lives of the men she has been involved with. She kills them, flees the scene and reinvents herself with a new image and a new identity.
The second character is DCI Peterson - the man in charge of tracking down and arresting Jennifer. He does everything he can to try and find out where she is and what she is doing but somehow Jennifer always manages to stay one step ahead of him.